Impact
At Augie’s Quest, our mission is to innovate toward a cure for ALS while improving the lives of those affected by this devastating disease. Through bold ideas, strategic investment, and relentless drive, we are accelerating progress where it matters most.
Accelerating Research: Thanks to your support, Augie’s Quest has already made a significant impact in the ALS community. It continues to fuel cutting-edge ALS research across genetics, biomarkers, and disease biology—advancing breakthrough discoveries and accelerating the development of targeted therapies. By investing in the most promising scientific approaches and translational research, we help move innovations from the lab into clinical trials faster—bringing us closer to stopping, reversing, and curing ALS.
Empowering Innovation: We believe that collaboration is key to unlocking the mysteries of ALS. We unite and support leading scientists, clinicians, and institutions -fostering collaboration and equipping them with the resources needed to move innovative ideas from lab to life-changing treatments.
Inspiring Action & Raising Awareness: By actively engaging the ALS community and passionate advocates, we amplify lived experiences to build a powerful movement that drives urgency, fuels innovation, and inspires lasting change.
We’ve made huge strides in the fight to cure ALS.
The AQ TRC was created in 2021 to discover new candidate drugs to slow, stop, or even reverse ALS disease progression. This grant has empowered ALS TDI researchers to achieve significant progress in understanding ALS, advancing drug discovery, and bridging the gap between research and treatment. By studying cells from people with ALS, the team has uncovered key biological processes driving disease onset and progression and identified high-quality drug candidates. These efforts have brought potential therapies closer to clinical application.
The Champion Insights Program is a focused research initiative, led by Answer ALS and Augie’s Quest to Cure ALS, designed to better understand why certain populations, such as military personnel, first responders, and high-performing athletes, are diagnosed with ALS at higher rates than the general public. These individuals have a greater chance of developing ALS, and we need to understand why. Thanks to MDA and Axe ALS for joining this initiative.
Scientific breakthroughs in genetics, biomarkers, and disease biology have created more promising treatment paths than ever before, and the infrastructure to test and advance them is critical. Augie’s Quest is funding the work of its research partner, ALS Therapy Development Institute, to turn discovery into action—building the systems, expertise, and urgency needed to accelerate therapies to patients and expand their research facilities.
“We owe much of our progress and ability to expand this transformative, essential research to Augie’s Quest.”
Fernando Vieira, MD, CEO & Chief Science Officer, ALS Therapy Development Institute
Augie’s Quest gifted $100,000 at Duke to research how the microbiome could affect ALS progression. Led by Richard Bedlack, M.D., Ph.D. , these studies could show if microbes in the gastrointestinal tract influence the speed of progression in ALS. In the intestinal microbiome transplant study, patients are currently being enrolled.
Augie’s Quest funds a dedicated position at UC Irvine ALS Clinic to strengthen patient care. In 2006, Augie’s Quest made an initial, catalytic donation that helped establish the ALS clinic at UCI Health and has enjoyed a long-standing relationship through patient referrals, collaboration, and ongoing commitment to the ALS community.
Augie’s Quest is proud to sponsor Her ALS Story’s Warrior Weekend. This community of over 100 women diagnosed with ALS before age 35 raise awareness and foster a supportive space to live their best lives. The multi-day retreat brings members together from all over the country to create life-changing connections and strengthen the community.
