This year has been a challenging one for our Quest with the loss of our inspiration and co-founder, Augie Nieto.
Our mission to find a cure for ALS (Amyotrophic Lateral Sclerosis) and improve the lives of those affected by this devastating disease remains our top priority.
We’re proud of the progress made this year at the Augie’s Quest Translational Research Center. Here are just some of the ways your support has made a tangible impact:
1) Using advanced cell biology techniques, the Augie’s Quest Translational Research Center (AQ TRC) initiated collaborative studies to explore two new drug targets – medicine intervention points – in motor neurons from people with ALS grown in the the lab.Developed new techniques for growing and studying axons – the long connections between neurons and muscles – in the lab.
These long connections break down in ALS. Understanding how they break down and discovering ways to stop that is important for developing effective treatments.
2) Initiated important studies of the how cells from people with ALS handle or mishandled critical RNA molecules. RNA molecules carry the instructions from human genes to the rest of the cell so that the cells can function properly. This is impaired in ALS and will likely need to be repaired. Scientists in the AQ TRC are exploring treatments that might address this dysfunction.As the end of 2023 approaches, we urge you to make your tax-deductible donation and help change the future for countless people living with ALS, their families, caregivers, and friends.
Incurable is Unacceptable. Together, we can create a future without ALS.
Thank you for your friendship and support,
Team Augie’s Quest to Cure ALS